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Optimal folate and B vitamin intakes are associated with healthy neurological function as well as cardiovascular support.*1,2 Each B-vitamin exists in multiple forms, often referred to as vitamers. Active forms of vitamers are those that can be directly utilized by the body immediately. Active B-Complex features a potent blend containing the active forms of Vitamins B2, B6, B12, as well as Quatrefolic®-branded methylfolate (the bioactive form of folate). Free from top 8 allergens.




B-vitamins play essential roles in many functions of the body. Vitamin B1 (as Thiamin) and Vitamin B2 (Riboflavin as riboflavin-5'-phosphate) serve as coenzymes essential for cell function, growth and energy production.*1 Vitamin B6 (as pyridoxal-5-phosphate and pyridoxine HCl) has an essential role in the synthesis of neurotransmitters, including serotonin, dopamine and gamma-aminobutyric acid (GABA).*3 Folate has essential roles in nervous system and immune system function.*1,4 Vitamin B12 (as methylcobalamin) is essential for nervous system function, playing particular roles in myelin synthesis and nerve metabolism.*5



  • Kennedy DO et al. Nutrients. 2016;8(2):68.
  • Wald DS et al. BMJ. 2002;325(7374):1202.
  • Stover PJ et al. Adv Nutr. 2015;6(1):132-3.
  • Maggini S et al. Nutrients. 2018;10(10):1531.
  • Calderon-Ospina CA et al. CNS Neurosci Ther. 2020;26(1):5-13.


* For homeopathic products: these indications are based solely on traditional homeopathic use. They have not been evaluated by the Food & Drug Administration.
* For dietary supplements: this statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Active B-Complex 60 Capsules

  • Serving Size:  2 capsules              Amount/Serving                      %DV

    Total Carbohydrate                            <1 g                                              <1%†

    Thiamin (as thiamin HCl)                 50 mg                                          4,167%

    Riboflavin                                               50 mg                                         3,846%

    (as riboflavin-5'-phosphate and Vitamin B2)

    Niacin (as niacinamide)                    100 mg                                        625%

    Vitamin B6                                               50 mg                                        2,941% 

    (as pyridoxal-5'-phosphate and pyridoxine HCl)

    Folate (837 mcg Quatrefolic®           800 mcg DFE                         200%

    brand  (6S)-5-methyltetrahydrofolate glucosamine salt)

    Vitamin B12 (as methylcobalamin)   1,000 mcg                         41,667%

    Biotin                                                              300 mcg                             1,000%

    Pantothenic Acid                                       100 mg                                2,000%

    (as calcium D-pantothenate)

    Choline (as choline bitartrate                 **                                             45%

    Inositol                                                            250 mg                                     **

    ** Daily Value (DV) not established

    †Percent daily value is based on a 2000 calorie diet

    Other Ingredients

    plant-derived capsule (hypromellose), cellulose, ascorbyl palmitate, silica

    Active B-Complex Does Not Contain:  Gluten, Soy, Dairy products, wheat, artficial flavors or artificial colors

  • Active B-Complex Directions and/or Dosage

    Adults take 1 or 2 capsules daily, or as recommended by a healthcare professional.


    If you are pregnant, nursing, or taking taking prescription drugs, consult a healthcare professional before use.

    Precautions and Safety Warnings

    It is recommended that you consult with a health-care practitioner prior to taking Integrative Therapeutics supplements. If you are pregnant, nursing, or taking presciption medications consult your healthcare professional prior to use.

    Keep out of reach of children.

    Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

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